Instructions and Frequently Asked Questions

Preoperative Instructions:

Postoperative Instructions:


Alternate to narcotics for post-operative pain management:


We are proud to let you know that this is an opioid-reducing office. What does that mean for you? Simply put, if you want pain management for oral or face and jaw surgery that doesn’t involve opioids, we have an option for you. The solution we offer—non-opioid EXPAREL—provides continuous long-lasting pain relief through the critical few days after surgery.
EXPAREL is injected during surgery while you’re still numb, and it works directly where you have your surgery to provide extended pain relief before you feel any postsurgical pain. Unlike opioids, which affect your whole body, EXPAREL provides targeted pain relief. More importantly, EXPAREL does not contain narcotics and is not addictive. It is also safe for a pediatric population.
We appreciate that not everyone wants opioids to manage their pain. Talk to us about non-opioid EXPAREL for pain management and visit to learn more.


EXPAREL is indicated for single-dose infiltration in patients aged 6 years and older to produce postsurgical local analgesia and in adults as an interscalene brachial plexus nerve block to produce postsurgical regional analgesia. Safety and efficacy have not been established in other nerve blocks.

Important Safety Information
EXPAREL should not be used in obstetrical paracervical block anesthesia.
In studies in adults where EXPAREL was injected into a wound, the most common side effects were nausea, constipation, and vomiting.
In studies in adults where EXPAREL was injected near a nerve, the most common side effects were nausea, fever, and constipation.
In the study where EXPAREL was given to children, the most common side effects were nausea, vomiting, constipation, low blood pressure, low number of red blood cells, muscle twitching, blurred vision, itching, and rapid heartbeat.
EXPAREL can cause a temporary loss of feeling and/or loss of muscle movement. How much and how long the loss of feeling and/or muscle movement depends on where and how much of EXPAREL was injected and may last for up to 5 days.
EXPAREL is not recommended to be used in patients younger than 6 years old for injection into the wound, for patients younger than 18 years old for injection near a nerve, and/or in pregnant women.
Tell your health care provider if you or your child has liver disease, since this may affect how the active ingredient (bupivacaine) in EXPAREL is eliminated from the body.
EXPAREL should not be injected into the spine, joints, or veins.
The active ingredient in EXPAREL can affect the nervous system and the cardiovascular system; may cause an allergic reaction; may cause damage if injected into the joints; and can cause a rare blood disorder.

Full Prescribing Information is available at
©2022 Pacira Pharmaceuticals, Inc., a wholly owned subsidiary of Pacira BioSciences, Inc. All rights reserved. PP-EX-US-7968 09/22